Business Lead Data Governance Office
Twist Bioscience Open · verified Oct 24, 2026 At a glance
Senior Data Architecture & Governance role at Twist Bioscience. South San Francisco · $130,678–$192,178 base.
dataroles summary, based on the employer's posting.
What you'll do
- Guide SAP MDG setup across business partner, customer/vendor and material data, with financial data planned later
- Shape MDG data models, user screens, approval flows and replication paths, then connect them to SAP and analytics systems
- Create validation and duplicate-detection rules, and set up profiling, remediation and data quality scoring for core data
- Launch the governance office, defining its charter, council, stewardship roles, approval paths, policies and data standards
- Track governance measures and data health, coordinating with BI leadership on reporting, analytics and compliance needs
What you bring
- A bachelor’s degree in computer science, information systems, business intelligence or another related field
- At least eight years in SAP data management, including four or more years leading end-to-end SAP MDG implementations
- A record of building and running a data governance office and putting stewardship practices into operation
- Experience managing directly and indirectly, plus strong collaboration across teams
- Understanding of how master data governance shapes BI reporting, data warehouses and enterprise analytics
Who this fits
This senior role suits someone who can lead SAP MDG delivery while establishing governance processes and stewardship across teams. It is hybrid in South San Francisco, California, and calls for both direct and indirect management experience.
From the employer
Business Lead Data Governance Office (Hybrid in South San Francisco, CA)
Summary
Reporting directly to the Director of Business Intelligence, the SAP Master Data
Governance (MDG) Lead will provide business processes expertise to the end-to-end
architecture, implementation, and operational strategy of our enterprise master data ecosystem.
In this role, you will bridge technical execution, analytics strategy and business
process—helping to implement the SAP MDG platform, creating data quality rules, and initially
establishing a SAP Data Governance Office to ensure high data integrity, seamless reporting,
and single-source-of-truth analytics across the organization.
Key Responsibilities
SAP MDG Build & Technical Architecture
- Participate and add expertise to the end-to-end implementation and configuration
of SAP MDG domains (Business Partner, Customer/Vendor, Material, at a later
time Financials). - Design custom data models, UI floorplans (FPM), change request workflows
(BRF+), and Data Replication Frameworks (DRF). - Partner with BI and enterprise architecture teams to integrate MDG with SAP
S/4HANA, analytics platforms, data warehouses, and downstream legacy
systems.
Rule Creation & Data Quality Management
- Define and enforce data validation rules, duplicate check algorithms, and
business logic within the SAP MDG platform. - Establish automated data profiling, continuous remediation processes, and data
quality scoring across core master data domains. - Define and monitor data governance KPIs, completion cycle times, and data
health dashboards in alignment with reporting goals.
Governance Office & Stewardship Leadership
- Build and formalize the Enterprise Data Governance Office, defining its charter,
operating model, and cross-functional council. - Establish enterprise data stewardship frameworks, defining clear roles (Data
Owners, Stewards, Custodians) and approval matrices. - Author data policies, standard operating procedures (SOPs), data dictionary
standards, and data lineage documentation. - Partner with the Director of Business Intelligence to align data governance
frameworks with business reporting, analytics strategy, and regulatory
compliance.
Qualifications & Requirements
- Bachelor’s degree in Computer Science, Information Systems, Business Intelligence, or a related field.
- 8+ years Experience in SAP Data Management, with 4+ years leading full-lifecycle SAP MDG implementations.
- Proven track record in both direct and indirect management.
- Successful collaboration experience is a must.
- Proven track record of establishing and managing a Data Governance Office and operationalizing data stewardship models.
- Solid understanding of how master data governance directly impacts BI reporting, data warehousing, and enterprise analytics.
About Twist Bioscience
Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.
At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.
Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.
The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.San Francisco Bay Area Pay Range$130,678—$192,178 USD
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